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The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research)

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Description:The transformation of a normal cell into a cancer cell is not a sudden but a slow continuous process which may take years. A systematic study of the morphological and structural changes that take place during this cellular transformation has only become possible since methods were developed to induce a high incidence of tumors in experimental animals. The growth of such tumors can be followed during all stages of their development. For several reasons, rat liver has proved to be particularly suitable. For more than thirty years it has been known that one can induce tumors in rat liver experimentally with many different substances. The azo dyes which were used originally (YOSHIDA, 1932; KINOSITA, 1937) have since been replaced by more potent carcinogens. The recently discovered nitrosamines, dimethylnitrosamine (MAGEE and BARNES, 1956), diethylnitrosamine (SCHMAHL et aI., 1960) and N-nitrosomorpholine (DRUCKREY et aI., 1961) should be mentioned in this context. Used in the proper dose, these carcinogens lead within a few months to the formation of multicentric hepatomas in practically 100 Ufo of the experimental animals, and are therefore a very useful tool for studies of the cytogenesis of cancer (see BUCHNER, 1961; GRUND MANN, 1961; GRUNDMANN and SIEBURG, 1962; OEHLERT and HARTJE, 1963; BAN NASCH and MULLER, 1964). The liver parenchyma as such offers a very big technical advantage because it consists of a rather homogenous cell population."We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research). To get started finding The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research), you are right to find our website which has a comprehensive collection of manuals listed.
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ISBN: 354004308X

Description: The transformation of a normal cell into a cancer cell is not a sudden but a slow continuous process which may take years. A systematic study of the morphological and structural changes that take place during this cellular transformation has only become possible since methods were developed to induce a high incidence of tumors in experimental animals. The growth of such tumors can be followed during all stages of their development. For several reasons, rat liver has proved to be particularly suitable. For more than thirty years it has been known that one can induce tumors in rat liver experimentally with many different substances. The azo dyes which were used originally (YOSHIDA, 1932; KINOSITA, 1937) have since been replaced by more potent carcinogens. The recently discovered nitrosamines, dimethylnitrosamine (MAGEE and BARNES, 1956), diethylnitrosamine (SCHMAHL et aI., 1960) and N-nitrosomorpholine (DRUCKREY et aI., 1961) should be mentioned in this context. Used in the proper dose, these carcinogens lead within a few months to the formation of multicentric hepatomas in practically 100 Ufo of the experimental animals, and are therefore a very useful tool for studies of the cytogenesis of cancer (see BUCHNER, 1961; GRUND MANN, 1961; GRUNDMANN and SIEBURG, 1962; OEHLERT and HARTJE, 1963; BAN NASCH and MULLER, 1964). The liver parenchyma as such offers a very big technical advantage because it consists of a rather homogenous cell population."We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research). To get started finding The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research), you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research)

The Cytoplasm of Hepatocytes during Carcinogenesis: Electron- and Lightmicroscopical Investigations of the Nitrosomorpholine-intoxicated Rat Liver (Recent Results in Cancer Research)

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