Description:Reelin glycoprotein is a serine protease with important roles in embryogenesis and during adult life. Reelin mutations or deficiency of the protein product could cause abnormal cortical development and reelin signaling impairment in brain. Reelin abnormalities in several neurospychiatric disorders, such as autism, schizophrenia, mood disorders and lissencephaly, may provide mechanistic explanations for etiologies of these disorders. There is also emerging data indicating the feasibility of using various medications (valproic acid, olanzapine) to increase mRNA/protein levels for reelin and/or gene therapy to prevent or treat reelin deficiencies observed in the above-mentioned disorders.This comprehensive and integrative book examines the role that reelin plays in the etiology of various neuropsychiatric disorders, including schizophrenia and autism.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Reelin Glycoprotein: Structure, Biology, and Roles in Health and Disease. To get started finding Reelin Glycoprotein: Structure, Biology, and Roles in Health and Disease, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.
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0387767614
Reelin Glycoprotein: Structure, Biology, and Roles in Health and Disease
Description: Reelin glycoprotein is a serine protease with important roles in embryogenesis and during adult life. Reelin mutations or deficiency of the protein product could cause abnormal cortical development and reelin signaling impairment in brain. Reelin abnormalities in several neurospychiatric disorders, such as autism, schizophrenia, mood disorders and lissencephaly, may provide mechanistic explanations for etiologies of these disorders. There is also emerging data indicating the feasibility of using various medications (valproic acid, olanzapine) to increase mRNA/protein levels for reelin and/or gene therapy to prevent or treat reelin deficiencies observed in the above-mentioned disorders.This comprehensive and integrative book examines the role that reelin plays in the etiology of various neuropsychiatric disorders, including schizophrenia and autism.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Reelin Glycoprotein: Structure, Biology, and Roles in Health and Disease. To get started finding Reelin Glycoprotein: Structure, Biology, and Roles in Health and Disease, you are right to find our website which has a comprehensive collection of manuals listed. Our library is the biggest of these that have literally hundreds of thousands of different products represented.