Read Genetic Polymorphism and Disease

Genetic Polymorphism and Disease

Syed Sameer Aga

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Description:Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases especially cancers, cardiovascular diseases, immune disorders, neurological pathologies. This book collates the reviews on the roles played by polymorphisms in critical metabolic, signal transduction, cell cycle or DNA repair genes either directly or indirectly in the disease mechanisms. The focus is on various techniques for identifying the various Single Nucleotide Polymorphisms (SNPs). Polymorphism studies document the affect SNPs, and their expressions have upon the functionality of the enzymes, proteins.Key Features1) General description of the Genetic Polymorphism and its various types2) Discuss the role of Genetic Polymorphisms in modulating risk of various human diseases3) Discuss various molecular techniques used for detecting GPs4) Discuss the role of SNPs in modulating the susceptibility of human diseases5) Genetic basis for individual variations in response to therapeuticsWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Genetic Polymorphism and Disease. To get started finding Genetic Polymorphism and Disease, you are right to find our website which has a comprehensive collection of manuals listed.
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ISBN: 1000688216

Description: Genetic polymorphisms are important determinants of phenotypic variations and may modulate the risk to or even cause various diseases including genetic disorders and multifactorial diseases. Genetic polymorphisms also serve as important genetic, population and evolutionary markers that allow the study of genetic and evolutionary aspects of individuals, populations and organisms and aid in tracing the evolutionary and parental lineages. Genetic polymorphisms in low penetrance genes are responsible for the alterations in the gene expression of critical signal transduction proteins and metabolic enzymes. Some of these polymorphisms are linked to increased susceptibility to various diseases especially cancers, cardiovascular diseases, immune disorders, neurological pathologies. This book collates the reviews on the roles played by polymorphisms in critical metabolic, signal transduction, cell cycle or DNA repair genes either directly or indirectly in the disease mechanisms. The focus is on various techniques for identifying the various Single Nucleotide Polymorphisms (SNPs). Polymorphism studies document the affect SNPs, and their expressions have upon the functionality of the enzymes, proteins.Key Features1) General description of the Genetic Polymorphism and its various types2) Discuss the role of Genetic Polymorphisms in modulating risk of various human diseases3) Discuss various molecular techniques used for detecting GPs4) Discuss the role of SNPs in modulating the susceptibility of human diseases5) Genetic basis for individual variations in response to therapeuticsWe have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Genetic Polymorphism and Disease. To get started finding Genetic Polymorphism and Disease, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Genetic Polymorphism and Disease

Genetic Polymorphism and Disease

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