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Dynamic Analysis of Enzyme Systems

Katsuya Hayashi

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Description:This book is concerned with a quantitative analysis of dynamic behavior of various enzymatic reaction systems by computer simulation. The authors and coworkers have been engaged in cooperative research since 1975, seeking to clarify the catalytic and regulatory characteristics of enzymatic reactions in vivo and control mechanisms suitable for enzyme technology. Rather than "enzyme kinetics" generally known in enzymol· ogy, this research has employed an approach called "enzyme dynamics" which concentrates on the exact schematic representation of an actual reac tion mechanism, derivation of rate equation on the basis of the scheme, and computer simulation of its dynamic behavior (numerical solution of the rate equation and explanation of kinetic and regulatory properties of the enzymatic reaction). A rate equation representing the behavior of enzymatic reactions is gen erally expressed by a set of nonlinear differential equations. The analytic solution of rate equations is therefore impossible in general, making it necessary to introduce some approximations in order to analyze the exper· imental data in enzyme kinetics. For example, under an assumption of excess substrate against enzyme in a closed system, we commonly use the linear approximation for the early period of reaction, the quasi-steady state approximation based on putative maintenance of steady state in en zyme species, and the rapid-equilibrium approximation assuming instantane ous equilibration in complex formation and between complexes. The kinetic characteristics obtained by these approximations do not always reflect the dynamic behavior of actual enzymatic reactions.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Dynamic Analysis of Enzyme Systems. To get started finding Dynamic Analysis of Enzyme Systems, you are right to find our website which has a comprehensive collection of manuals listed.
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Pages: 392

Format: PDF, EPUB & Kindle Edition

Publisher: Springer

Release: 1986

ISBN: LYJOAQAAIAAJ

Description: This book is concerned with a quantitative analysis of dynamic behavior of various enzymatic reaction systems by computer simulation. The authors and coworkers have been engaged in cooperative research since 1975, seeking to clarify the catalytic and regulatory characteristics of enzymatic reactions in vivo and control mechanisms suitable for enzyme technology. Rather than "enzyme kinetics" generally known in enzymol· ogy, this research has employed an approach called "enzyme dynamics" which concentrates on the exact schematic representation of an actual reac tion mechanism, derivation of rate equation on the basis of the scheme, and computer simulation of its dynamic behavior (numerical solution of the rate equation and explanation of kinetic and regulatory properties of the enzymatic reaction). A rate equation representing the behavior of enzymatic reactions is gen erally expressed by a set of nonlinear differential equations. The analytic solution of rate equations is therefore impossible in general, making it necessary to introduce some approximations in order to analyze the exper· imental data in enzyme kinetics. For example, under an assumption of excess substrate against enzyme in a closed system, we commonly use the linear approximation for the early period of reaction, the quasi-steady state approximation based on putative maintenance of steady state in en zyme species, and the rapid-equilibrium approximation assuming instantane ous equilibration in complex formation and between complexes. The kinetic characteristics obtained by these approximations do not always reflect the dynamic behavior of actual enzymatic reactions.We have made it easy for you to find a PDF Ebooks without any digging. And by having access to our ebooks online or by storing it on your computer, you have convenient answers with Dynamic Analysis of Enzyme Systems. To get started finding Dynamic Analysis of Enzyme Systems, you are right to find our website which has a comprehensive collection of manuals listed.
Our library is the biggest of these that have literally hundreds of thousands of different products represented.

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Dynamic Analysis of Enzyme Systems

Dynamic Analysis of Enzyme Systems

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Keieisha o sapoÌ„to suru keiei koÌ„chi nyuÌ„mon

Keieisha o sapoÌ„to suru keiei koÌ„chi nyuÌ„mon

Gijutsushi dainiji shiken joÌ„gesuidoÌ„ bumon kaitoÌ„ ronbun jirei hyakusen

Gijutsushi dainiji shiken joÌ„gesuidoÌ„ bumon kaitoÌ„ ronbun jirei hyakusen

Rika wa kawatashiki noÌ„to de shoÌ„bu : anata no jugyoÌ„ de katsuyaku suru choÌ„uttori mihon

Rika wa kawatashiki noÌ„to de shoÌ„bu : anata no jugyoÌ„ de katsuyaku suru choÌ„uttori mihon

Jinzai shokai no puro ga oshieru hattatsu shogai no hito ga katsuyaku suru tame no hinto.

Jinzai shokai no puro ga oshieru hattatsu shogai no hito ga katsuyaku suru tame no hinto.